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KMID : 0374019850080010069
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Ewha Medical Journal
1985 Volume.8 No. 1 p.69 ~ p.75
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A Case of Gilberts Syndrome Combined with Hemolysis
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Abstract
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Gilbert´s Syndrome is the name most frequentlyused to describe a condition which has been called constitutional hepatic dysfunction, familial nonhemolytic jaundice or -icterus intermittens juvenilis. It is characterized by a benign, persistent, but variable elevation of the plasma unconjugated bilirubin.
A 27- year - old man was admitted because of general malaise, anorexia, sore throat and slight icteric sclera. On physical examination, there were mild icteric sclera and slightly injected pharynx. The liver was palpable 1 finger breadth BRCM and the spleen was also palpable I finger breadth BLCM Hematologic studies revealed slight anemia with slightly elevated corrected reticulocyte count. Liver function tests were normal except for slightly elevated serum total bilirubin. Histologic findings of the liver showed nonspecific findings of mild cholestasis. Reduction in caloric intake to 300 calory a day for 72 hours resulted in a significant increase in the plasma bilirubin concenteration ( especially. unconjugated form) in this patient
Now he has no subjective symptoms and leads a normal activity without specific treatement.
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KEYWORD
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